Practical Reviews

HIV Myositis Closely Resembles Inclusion-Body Myositis


Background: Typical features of polymyositis (PM) include subacute onset, weakness of proximal limb muscles, very high serum creatine kinase (CK), endomysial lymphocytic inflammation, and response to immunosuppressive therapy. Typical features of inclusion-body myositis (IBM) include onset after the age of 50 years; insidious onset and slowly progressive course; weakness of quadriceps and distal muscles, especially wrist and finger flexors; moderately high serum CK; rimmed vacuoles more...
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