Triple Receptor-Negative Breast Cancer -- A Bad Actor With Suspicious Imaging Features

Background: Triple receptor-negative breast carcinoma is described as being an aggressive form of breast cancer characterized by a lack of progesterone, estrogen, and human epidermal growth factor 2 (HER2) receptors on histologic analysis. These cancers have been shown to have poorer clinical outcomes with greater likelihood of distant metastatic disease. Objective: To describe the imaging findings of triple receptor-negative breast cancer. Design/Methods: Over a 9-year retrospective period, patients at a single institution who had been diagnosed with triple receptor-negative breast cancer were identified through a search in the electronic medical record system. Clinical and imaging data were reviewed and information such as patient age at diagnosis, method of detection, tumor size at diagnosis, and findings on mammography and ultrasound was recorded. Furthermore, 2 radiologists participating in the study independently retrospectively reviewed the images for those patients with tripl more...