Practical Reviews

Waking Up to General Anesthesia -- Is It Not Transient After All?

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Background: Each year, millions of children require surgery with general anesthesia. Over the past decade, a growing body of work from animal studies in a wide variety of species, including primates, has suggested that anesthetics may have long-term effects in the developing brain on learning and cognitive behavior. Given the implications from these animal studies, cohort and epidemiological studies have attempted to address the effects of anesthesia exposure in humans prior to age more...
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