Practical Reviews

ADC Is Poor Surrogate for Active Inflammation in Crohn Disease


Background: Crohn disease has many imaging manifestations including causing restricted diffusion of bowel. However, it is unclear how much useful this imaging finding is. Objective: To determine if apparent diffusion coefficient (ADC) can be used as a surrogate for disease activity in patients with Crohn disease. Design: Prospective study. Participants: 28 pediatric patients with newly diagnosed, untreated Crohn disease. Methods: Imaging and laboratory markers were conducted at dia more...
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