Practical Reviews

MCI -- Examining CSF Tau and Longitudinal Changes in WM Integrity


Objective: To evaluate the relationship between pathologic cerebrospinal fluid (CSF) tau levels and changes in white matter (WM) integrity in patients with mild cognitive impairment (MCI). Design: 39 patients with MCI (19 women, 20 men; mean age, 59.79 years) and 16 control subjects (10 women, 6 men; mean age, 61.69 years) were included in this prospective study between 2005 and 2009. Methods: Patients underwent lumbar puncture as part of the clinical evaluation; it was not availab more...
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