Practical Reviews

Midazolam Good Pediatric Agent, but Needs Flavoring


Midazolam (Versed ® ) is a benzodiazepine that is a very potent anxiolytic, and it is a strong amnestic agent. It is a good option for providing preoperative or intraoperative sedation (procedural sedation). Mechanism of Action: Midazolam is a benzodiazepine receptor agonist and works by positive allosteric modulation. Metabolism: Midazolam is broken down in the liver, and it has an active metabolite: alpha-hydroxymidazolam. This metabolite, even though it is active, has a very sho more...
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