Practical Reviews

Most Anal Carcinomas Are SCCs Related to HPV Infection

Background: Anal cancer is less common than other gastrointestinal tract malignancies. It is most often squamous cell carcinoma (SCC) in the setting of human papillomavirus (HPV) infection but other types also exist. Objective: To review different anal and perianal tumors. Anatomy: The anal canal extends down to the anal verge approximately 4 cm. The anal margin is perianal skin surrounding the anal verge for 5 cm. There is an internal and external anal sphincter. The dentate line more...
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