LCIS Is Not Cancer, But It's Not Benign Either

Background: The pathologic diagnosis of lobular carcinoma in situ (LCIS) is a frustrating result of core needle biopsy since there is no clear well-documented approach in the subsequent management of these patients. LCIS has been shown to increase the patient's overall chance of developing breast cancer over the course of her lifetime, but there is no widely accepted method on how to deal with this possibility. Objective: To evaluate the efficacy of surgical excisional biopsy after image-guided core needle biopsy yields a pathologic result of LCIS. Methods: Over an 11-year retrospective period, all image-guided core needle biopsies at a single institution were identified. Those that yielded a diagnosis consisting purely of LCIS at core biopsy were included. For each case, patient demographics were gathered including menopausal status, breast density composition, and whether the patient had a personal or family history of breast cancer. How the targeted lesion that yielded LCIS manife more...