Practical Reviews

Major Bleeding Risk Higher in Older Patients on Antiplatelet Tx

Background: Lifelong antiplatelet therapy is recommended for patients who have had ischemic vascular events. As upper gastrointestinal (GI) bleeding is a serious complication of this therapy, but has a low fatality rate in aspirin trials, measures to prevent bleeding are not widely used. Objective: To assess the type, severity, outcome (disability or death), and time course of the bleeding on antiplatelet treatment for secondary prevention in patients of all ages. Methods: The Oxfo more...
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