Practical Reviews

Patients With HE Show Diffuse Changes in Resting Brain Activity


Objective: To evaluate spatial patterns of the amplitude of low-frequency fluctuation (ALFF) in patients with varying degrees of hepatic encephalopathy (HE) and to correlate these findings with clinical markers of HE. Design/Participants: Prospective study of 46 patients (34 male and 12 female; 15 with severe HE, 14 with minimal HE, and 17 healthy controls) who were recruited into the study between December 2007 and December 2009. Methods: Diagnosis and classification of overt and more...
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