Practical Reviews

131I-131 Ablation After Thyroidectomy Recommended for DTCs


Background: The 2015 American Thyroid Association guidelines for differentiated thyroid cancer (DTC) recommend 131 I ablation following thyroidectomy for higher-risk differentiated thyroid cancers. The optimal dose is not clear but recent trends favor lower doses based on published randomized controlled trials (RCTs) and a meta-analysis, which suggested that low-dose radioiodine (30 mCi) is associated with ablation success rates similar to high-dose therapy (100 mCi). No such RCTs more...
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