Increase Good, Decrease Bad -- Tomosynthesis May Improve Detection of Breast Ca

Background: Mammographic screening is the most widely recommended screening modality for the detection of breast cancer, although mammography has well-documented limitations, including the problem of overlapping fibroglandular tissue that may obscure a cancer. By obtaining images of the breasts at different depths and displaying them as multiple slices, digital breast tomosynthesis has been designed to decrease the amount of overlapping fibroglandular breast tissue that may obscure a pertinent finding. Objective: "To assess cancer detection rates, false-positive rates before arbitration, positive predictive values for women recalled after arbitration, and the type of cancers detected with use of digital mammography alone and combined with tomosynthesis in a large prospective screening trial." Methods: Over a 1-year prospective period, the research team of the Oslo screening program (part of the Norwegian Breast Cancer Screening Program) invited patients to undergo screening for breas more...