Practical Reviews

Intranasal Midazolam for Emergencies Without Fasting


Background: In South Africa, IV sedation is very limited. As a result, children presenting for emergency dental extractions may be traumatized. Oral sedation (OS) has a longer onset and longer recovery time and is not the ideal route of administration in a busy emergency clinic. The onset of intranasally delivered drugs is 3 times faster than that of OS, because intranasal (IN) drugs bypass hepatic metabolism. In addition, the child cannot expectorate the medication. Objective: To more...
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