Practical Reviews

Pancreatic Cysts Are More Common in PKD2 Than PKD1 Mutations


Background: Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder affecting the kidneys and is a common cause of end-stage renal disease. However, this disease affects other organs, including the pancreas, with pancreatic cyst formation. Mutations of the PKD1 and PKD2 genes are responsible. Objective: To determine the prevalence of pancreatic cysts in ADPKD. Design: Retrospective study. Methods: 110 patients with ADPKD were enrolled along with a cohort matched more...
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