Practical Reviews

Misdiagnosis of Erythema Multiforme Is Common

Background: Erythema multiforme (EM) is an immune-mediated reaction characterized by target lesions on the skin. But, target lesions are not pathognomonic for EM; conditions showing a similar appearance include simple urticaria or Stevens-Johnson syndrome (SJS). Proper management of EM, or an alternate condition, depends on accurate diagnosis. Prior adult and pediatric studies suggest that EM is often misdiagnosed. Objective: To describe the diagnosis and management of pediatric EM more...
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