Practical Reviews

Are ALH and LCIS Similar Actors on the Cancer Stage?


Background: The term "lobular neoplasia" encompasses a spectrum of pathologic findings that include atypical lobular hyperplasia (ALH) and lobular carcinoma in situ (LCIS). Described as a proliferation of monomorphic cells in the terminal duct lobular unit, ALH is diagnosed when only a few acini are involved, and LCIS is diagnosed when the entire lobular unit is involved. A diagnosis of lobular neoplasia confers an increased risk of breast cancer by up to 10 times, and surgical exc more...
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