Practical Reviews

Move Over Epi -- DMED May Be Next Local Anesthesia Additive

Background: Dexmedetomidine is a selective alpha-2 adrenoreceptor agonist and is used as a procedural sedation agent. Recently it has been used in combination with local anesthetics to enhance their effects. Objective: To compare the onset and duration of anesthesia when dexmedetomidine is used as an adjunct. Methods: 10 healthy volunteers aged between 10 and 25 years undergoing orthodontic extractions were recruited for this randomized, single-blinded pilot study. Subjects were sc more...
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